The Experimental Surgery Core (ESC) at CMIR brings unique expertise in surgical procedures, minimally invasive intervention, intraoperative imaging and life support. The Core also performs innovative research on novel fiberoptic sensing and diagnostic procedures.
Procedures performed by the Experimental Surgery Core (ESC):
- Orthotopic tumor cell implantation into lung, esophagus, stomach, liver, pancreas, adrenal gland, kidney, ovary, bladder, prostate, small bowel and colon
- Dual xenograft implantation of glioma and neural stem cells using a stereotatic apparatus
- Central catheterization of artery/vein, peripheral veno-punction (tail vein and retro-orbital)
- Delivery of therapeutics via gavage, IV, IP and IM injections, pump implantation. Intracerebral implantation of permanent device for continuous therapy
- Window chamber insertion and subcutaneous tumor implantation for repeated IVM imaging
- Murine cranial window for repeated IVM imaging of mouse brain
- Murine myocardial infarction
- Xenograft stem cell implants into infarcted myocardium
- Carotid artery isolation for imaging of atherosclerotic plaque using intravital microscopy
- Implantation of aorta telemetry device for continuous blood pressure measurements
- Surgically induced reno-vascular hypertension model by left heminephrectomy and right nephrectomy
- Surgically induced ureteropelvic junction (UPJ) obstruction
- Urinary stones model
- Murine stroke model
- Murine pulmonary thromboembolism model
- Selective lung intubation and mechanic ventilation for cardiothoracic surgery and imaging of small animals
- Intratracheal instillation of drugs and induction of various asthma models
- Murine esophagus (surgical) injury model and xenograft stem cells implantation
- Catheterization of pancreatic murine duct
- Isolation and imaging of peripheral and intra-abdominal lymph node
- Murine gastric-esophageal reflux model (esophagus-jejunostomy)
- Small animal endoscopy: thoracoscopy, bronchoscopy, mediatinoscopy, esophagoscopy, colonoscopy, cystoscopy and laparoscopy.
All service requests are project-based and processed through MIP.
