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Weissleder R, Pittet MJ
Imaging in the era of molecular oncology
Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079
Corsten MF, Shah K
Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare.
Lancet Oncol. 2008;9(4):376-84 - PMID: 18374291
Harisinghani M
Nanoparticle-enhanced MRI: are we there yet?
Lancet Oncol. 2008;9(9):814-815 - PMID: 18760237
Wurdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM
miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells.
Cancer Cell. 2008;14(5):382-393 - PMID: 18977327 - PMCID: PMC2597164
Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA
A secreted luciferase for ex vivo monitoring of in vivo processes.
Nat Methods. 2008;5:171-173 - PMID: 18204457 - PMCID: PMC2699561
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, Garcia-Echeverria C, Weissleder R, Mahmood U, Cantley LC, Wong KK
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415
Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R
Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma.
PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750
Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R.
Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis
Circulation. 2008;117:379-387 - PMID: 18158358 - PMCID: PMC2663426
Kircher M, Grimm J, Swirski FK, Libby P, Gerszten R, Allport J, Weissleder R
Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions.
Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289
Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R
Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis.
Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441
Nahrendorf M*, Sosnovik D*, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R
Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury.
Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051
Libby P, Nahrendorf M, Pittet MJ, Swirski FK
Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal.
Circulation. 2008;117(25):3168-70 - PMID: 18574058
Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne S, Blankesteijn M, Sosnovik D, Jaffer F, Tung CH, Weissleder R
Transglutaminase activity in acute infarcts predicts healing outcome and let ventricular remodelling : implications for FXIII therapy and antithrombin use in myocardial infarction
Eur Heart J. 2008;29:445-454 - PMID: 18276618
Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M
Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging.
J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468
Koh I, Hong R, Weissleder R, Josephson L
Sensitive NMR Sensors Detect Antibodies to Influenza.
Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198
McCarthy JR, Weissleder R
Multifunctional magnetic nanoparticles for targeted imaging and therapy.
Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936
Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K
Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity.
Gastroenterology. 2008;134(4):1028-37 - PMID: 18395084
Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation
J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification.
J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884
Pittet MJ, Mempel TR
Regulation of T-cell migration and effector functions: insights from in vivo imaging studies.
Immunol Rev. 2008;221:107-29 - PMID: 18275478
Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG
Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres.
ACS Nano. 2008;2(2):197-202 - PMID: 19206619
Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R
Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis.
Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A.
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis
Proc Natl Acad Sci U S A. 2008;:ePub
Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V
Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo.
Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726
Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R
Perturbational profiling of nanomaterial biologic activity.
Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702
Breckwoldt M*, Chen JW*, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz M, Weissleder R
Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase
Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593
Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R
Detection of early prostate cancer using a hepsin-targeted imaging agent.
Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884
Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK
Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin.
Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122
Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X
siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells.
Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568
Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R
Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model.
J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321
Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L
Simplified syntheses of complex multifunctional nanomaterials.
Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914
Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U
Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy.
Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096
Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M
Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies.
Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865
Sosnovik DE, Nahrendorf M, Weissleder R
Targeted imaging of myocardial damage.
Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275
Nahrendorf M, Sosnovik DE, Weissleder R
MR-optical imaging of cardiovascular molecular targets.
Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635
Sosnovik DE, Nahrendorf M, Weissleder R
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications.
Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271
Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ
Multimodality Cardiovascular Molecular Imaging, Part I
Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L
Slow Self-Activation Enhances The Potency of Viridin Prodrugs.
J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427
Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide.
Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233
Perez JM, Grimm J, Josephson L, Weissleder R
Integrated nanosensors to determine levels and functional activity of human telomerase.
Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593
Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A
MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators.
Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720
Law B, Tung CH
Structural modification of protease inducible preprogrammed nanofiber precursor.
Biomacromolecules. 2008;9:421-5 - PMID: 18177006
Hilderbrand SA, Kelly KA, Niedre M, Weissleder R
Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging.
Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288
Shao F, Weissleder R, Hilderbrand SA
Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation.
Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649
Devaraj N, Weissleder R, Hilderbrand S
Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging.
Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645
Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L
Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells.
Bioconjug Chem. 2008;19:130-137 - PMID: 17988080
Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE
Noninvasive imaging of apoptosis in cardiovascular disease.
Heart Fail Rev. 2008;13(2)::163-173 - PMID: 18074226 - PMCID: PMC2597223
Taktak S, Weissleder R, Josephson L
Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium.
Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273
Lasser T, Soubret A, Ripoll J, Ntziachristos V
Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion.
IEEE T Med Imaging. 2008;27(2):188-94 - PMID: 18334440
Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L
BRAF activation initiates but does not maintain invasive prostate adenocarcinoma.
PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248
Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K
Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth.
PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397
Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R
A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence.
J Urolology. 2008;179:1610-1614 - PMID: 18295253
Feldman AS, McDougal WS, Harisinghani MG
The potential of nanoparticle-enhanced imaging.
Urol Oncol. 2008;26(1):65-73 - PMID: 18190834
Salthouse C, Hilderbrand S, Weissleder R, Mahmood U
Design and demonstration of a small-animal up-conversion imager.
Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740
Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V
Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging.
J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169
Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ, Mueller PR
Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography.
Ann Thorac Surg. 2008;86:1131-8 - PMID: 18805147
Yip S, Shah K
Stem-cell based therapies for brain tumors.
Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097
Razansky D, Vinegoni C, Ntziachristos V
Polarization-sensitive optoacoustic tomography of optically diffuse tissues.
Opt Lett. 2008;33(20):2308-10 - PMID: 18923605
Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P
MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors.
Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144
Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P
Searching for a cure: Gene therapy for glioblastoma.
Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757
Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL
A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla.
Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273
Hong R, Cima MJ, Weissleder R, Josephson L
Magnetic microparticle aggregation for viscosity determination by MR.
Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908
Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP
Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model.
Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135
Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U
In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe.
Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813
Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS
Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis.
AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062
Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V
Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications.
J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214
Chang K, Jaffer F
Advances in fluorescence imaging of the cardiovascular system.
J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648
Salthouse CD, Weissleder R, Mahmood U
Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis.
IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943
Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M
Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON).
J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932
Osborn EA, Jaffer FA
Advances in molecular imaging of atherosclerotic vascular disease.
Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946
Boland GW, Guimaraes AS, Mueller PR
Radiology report turnaround: expectations and solutions.
Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594
Boland GW, Guimaraes AS, Mueller PR
The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization.
Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347
Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG
Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer.
Urology. 2008;71(4):708-12 - PMID: 18295316
Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S.
Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation
IEEE T Inf Technol B. 2008;12:569-578
Roedl JB, Blake MA, Holalkere NS, Mueller PR, Colen RR, Harisinghani MG
Lymph node staging in esophageal adenocarcinoma with PET-CT based on a visual analysis and based on metabolic parameters.
Abdom Imaging. 2008;34(5):610-7 - PMID: 18830663
Li CS, Harisinghani MG, Lin WC, Braschi M, Hahn PF, Mueller PR
Enhancement Characteristics of Ultrasmall Superparamagnetic Iron Oxide Particle Within the Prostate Gland in Patients With Primary Prostate Cancer.
J Comput Assist Tomogr. 2008;32:523-528 - PMID: 18664836
Miyazaki T, Aikawa E, Aikawa M
Biology of Cholesterol Lowering in Atherosclerotic Plaques
Immunol Endocrine and Metabolic Agents. 2008;8(2):105-115
Sosnovik DE
Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential.
Top Magn Reson Imaging. 2008;19:59-68 - PMID: 18690161 - PMCID: PMC2597277
Rusanescu G, Weissleder R, Aikawa E
Notch signaling in cardiovascular disease and calcification.
Curr Cardiol Review. 2008;4(3):148-56 - PMID: 19936191 - PMCID: PMC2780816
Salthouse C, Weissleder R, Mahmood U
Development of a Time Domain Fluorimeter (TDF) for Fluorescent Lifetime Multiplexing Analysis
2008;3:204-211
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