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Weissleder R.
Molecular Imaging in Cancer
Science. 2006;312:1168-1171 - PMID: 16728630
Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C
Particularities of the vasculature can promote the organ specificity of autoimmune attack.
Nat Immunol. 2006;7(3):284-92 - PMID: 16444258
Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Janne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies.
Cancer Cell. 2006;9(6):485-95 - PMID: 16730237
Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R
An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles.
Nat Mater. 2006;5(2):118-22 - PMID: 16444262
Mempel T, Pittet M, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Adrian U.
Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation
Immunity. 2006;25(1):129-41 - PMID: 16860762
Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC
Identification of the target self-antigens in reperfusion injury.
J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091
Aikawa E, Whittaker P, Farber M, Mendelson K, Padera R, Aikawa M, Schoen F
Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering.
Circulation. 2006;113:1344-52 - PMID: 16534030
Nahrendorf M, Hu K, Frantz S, Jaffer F, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed G, Jakob P, Rosenzweig A, Bauer W, Weissleder R, Ertl G.
Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction
Circulation. 2006;113(9):1196-1202 - PMID: 16505171
Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE
Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells.
Circulation. 2006;113(19):2301-12 - PMID: 16682613
Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R
Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis.
Circulation. 2006;114:1504-1511 - PMID: 17000904
Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P
Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo.
Circulation. 2006;114:55-62 - PMID: 16801460
Tannous B*, Grimm J*, Perry K, Chen J, Weissleder R, Breakefield X.
Metabolic Biotinylation of Cell Surface Receptors for in vivo Imaging
Nat Methods. 2006;3(5):391-396 - PMID: 16628210
Quinti L, Weissleder R, Tung CH
A Fluorescent Nanosensor for Apoptotic Cells
Nano Lett. 2006;6 (3):488-490 - PMID: 16522048
Jaffer F, Libby P, Weissleder R.
Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications
J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517
Ntziachristos V
Fluorescence Molecular Imaging.
Annu Rev Biomed Eng. 2006;8:1-33 - PMID: 16834550
Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J
Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2.
Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA
Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678
Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A.
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses
Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940
Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R
Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease.
Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459
Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R.
Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles
Nat Protoc. 2006;1(1):73-79
Khazaie K, von Boehmer H
The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer.
Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370
Choi YD, Weissleder R, Tung CH.
Selective antitumor effect of novel protease-mediated photodynamic agent
Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570
Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U
Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization.
Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355
McCarthy J, Jaffer F, Weissleder R.
A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications
Small. 2006;2(8-9):983-987 - PMID: 17193154
Sun EY, Weissleder R, Josephson L.
Continuous Analyte Sensing with Magnetic Nanoswitches
Small. 2006;(2) 10:1144-1147 - PMID: 17193579
Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palu G, Irimia D, Toner M, Weissleder R, Poznansky MC
Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control.
J Immunol. 2006;176(5):2902-14 - PMID: 16493048
Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD
Oligomerization of CXCL10 Is Necessary for Endothelial Cell Presentation and In Vivo Activity.
J Immunol. 2006;177:6991-8 - PMID: 17082614
Pittet M, Gati A, Le Gal F, Bioley G, Guillaume P, de Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Zippelius A
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
J Immunol. 2006;176:2330-6 - PMID: 16455990
Mahmood U
Can a clinically used chemoembolization vehicle improve transgene delivery?
Radiology. 2006;240(3):619-20 - PMID: 16926318
Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D
Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging.
Radiology. 2006;241(3):822-830 - PMID: 17114629
Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R
Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates
Radiology. 2006;240 (2):473-81 - PMID: 16864673
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA
Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging.
Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK
N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption.
Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079
Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U.
Fluorescent Nanoparticle Uptake for Brain Tumor Visualization
Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680
Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L.
Nanoparticle Imaging of Integrins on Tumor Cells
Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521
Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL
In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice.
Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300
Kelly KA, Waterman P, Weissleder R.
In vivo imaging of molecularly targeted phage
Neoplasia. 2006;8 (12):1011-1018
Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R
Molecular imaging of myocardial infarction.
J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries.
RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893
Law B, Quinti L, Choi YD, Weissleder R, Tung CH
A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity
Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814
Yuan H, Luo J, Weissleder R, Cantley L, Josephson L
Wortmannin-C20 Conjugates Generate Wortmannin.
J Med Chem. 2006;49(2):740-747 - PMID: 16420059
Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.
Multivalent effects of RGD peptides obtained by nanoparticle display
J Med Chem. 2006;49(20):6087-6093
Galande A, Hilderbrand S, Weissleder R, Tung CH.
Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core
J Med Chem. 2006;49(15):4715-20 - PMID: 16854078
Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO
Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.
Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122
Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
J Leukocyte biol. 2006;81(3):748-56 - PMID: 17178915
Montet X, Weissleder R, Josephson L.
Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas
Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396
Sun EY, Josephson L, Kelly KA, Weissleder R
Development of nanoparticle libraries for biosensing.
Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258
Galande A, Weissleder R, Tung CH.
Fluorescence Probe with a pH-Sensitive Trigger
Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452
Banerjee P, Weissleder R, Bogdanov A
Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery.
Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260
Montet X, Yuan H, Weissleder R, Josephson L
Enzyme-based visualization of receptor-ligand binding in tissues.
Lab Invest. 2006;86(5):517-25 - PMID: 16568109
Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA
Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer.
Lab Invest. 2006;86(6):599-609 - PMID: 16607378
Nahrendorf M, Weissleder R, Ertl G
Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction?
PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326
Law B, Weissleder R, Tung CH
Peptide-based Biomaterials for Protease-Enhanced Drug Delivery
Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747
Shah K, Breakefield XO
HSV Amplicon Vectors for Cancer Therapy.
Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187
Nahrendorf M, Streif J, Hiller K, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob P, Ertl G, Spindler M, Bauer W
Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics.
Am J Physiol-Heart C. 2006;290(6):H2516-21 - PMID: 16415075
Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R
In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging.
Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746
Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP
Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy.
Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601
Kelly KA, Clemons PA, Yu AM, Weissleder R
High throughput identification of phage-derived imaging agents
Mol Imaging. 2006;5(1):24-30 - PMID: 16779967
Sun EY, Josephson L, Weissleder R.
Clickable nanoparticles for targeted imaging
Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026
Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R
Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials
Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022
Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V
Normalized transillumination of fluorescent proteins in small animals.
Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030
Montet X, Rajopadhye M, Weissleder R.
An albumin-activated far-red fluorochrome for in vivo imaging
ChemMedChem. 2006;1(1):66-69 - PMID: 16892337
Choi YD, McCarthy J, Weissleder R, Tung CH
Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy
ChemMedChem. 2006;1(4):458-463 - PMID: 16892381
Choi Y, Weissleder R, Tung CH
Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate.
ChemMedChem. 2006;1:698-701 - PMID: 16902920
Ho NH, Weissleder R, Tung CH
Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate.
Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162
Niedre MJ, Turner GM, Ntziachristos V
Time-resolved imaging of optical coefficients through murine chest cavities.
J Biomed Opt. 2006;11(6):064017 - PMID: 17212540
Hsiao JK, Law B, Weissleder R, Tung CH
In-vivo imaging of tumor associated urokinase-type plasminogen activator activity.
J Biomed Opt. 2006;11(3):34013 - PMID: 16822063
Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA
Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy.
J Biomed Opt. 2006;11(2):21009 - PMID: 16674184
Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R
Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers.
AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509
Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R
Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization?
AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394
Ho NH, Weissleder R, Tung CH
Development of water-soluble far-red fluorogenic dyes for enzyme sensing
Tetrahedron. 2006;62:578-585
Soubret A, Ntziachristos V
Fluorescence molecular tomography in the presence of background fluorescence.
Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619
Ross R, Harisinghani M
Prostate cancer imaging-what the urologic oncologist needs to know.
Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222
Saksena MA, Saokar A, Harisinghani MG
Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging.
Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955
Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery.
J Neurosurg. 2006;105:445-54 - PMID: 16961141
Ross R, Harisinghani M
New clinical imaging modalities in prostate cancer.
Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116
Saokar A, Braschi M, Harisinghani M
Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging.
Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506
Weissleder R, Imhof H
Molecular imaging -a new emphasis in radiology
Radiologe. 2006;47(1):6-7 - PMID: 17136404
Deliolanis N, Lasser T, Niedre M, Soubret A, Ntziachristos V
In-vivo Lung Cancer Imaging in Mice using 360 degrees Free-space Fluorescence Molecular Tomography.
2006;1:2370-2372 - PMID: 17946109
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