CMIR - Publications

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Weissleder R

Scaling down imaging: molecular mapping of cancer in mice

Nat Rev Cancer. 2002;2:1-8 - PMID: 11902581

Ntziachristos V, Tung CH, Bremer C, Weissleder R

Fluorescence molecular tomography resolves protease activity in vivo

Nat Med. 2002;8:757-60 - PMID: 12091907

Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis

Cancer Cell. 2002;1:269-77 - PMID: 12086863

Perez JM, Josephson L, O'Loughlin T, Hogemann D, Weissleder R

Magnetic relaxation switches capable of sensing molecular interactions

Nat Biotechnol. 2002;20:816-20 - PMID: 12134166

Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D

Arthritis critically dependent on innate immune system players

Immunity. 2002;16:157-68 - PMID: 11869678

Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R

In vivo imaging of proteolytic activity in atherosclerosis

Circulation. 2002;105:2766-71 - PMID: 12057992

Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice

Gastroenterology. 2002;122:406-14 - PMID: 11832455

Pham W, Weissleder R, Tung CH

An azulene dimer as a near-infrared quencher

Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922

Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L

DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents

J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860

Jaffer FA, Tung CH, Gerszten RE, Weissleder R

In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe

Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227

Bremer C, Tung CH, Bogdanov A Jr, Weissleder R

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes

Radiology. 2002;222:814-8 - PMID: 11867806

Mahmood U, Tung CH, Tang Y, Weissleder R

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice

Radiology. 2002;224:446-51 - PMID: 12147841

Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2

Neoplasia. 2002;4:501-9 - PMID: 12407444 - PMCID: PMC1503664

Bogdanov AA Jr, Lin CP, Simonova M, Matuszewski L, Weissleder R

Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment

Neoplasia. 2002;4:228-36 - PMID: 11988842 - PMCID: PMC1531696

Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK

Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model

Neoplasia. 2002;4:3-8 - PMID: 11922388 - PMCID: PMC1503314

Ichikawa T, Hogemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP

MRI of transgene expression: correlation to therapeutic gene expression

Neoplasia. 2002;4:523-30 - PMID: 12407446 - PMCID: PMC1503666

Zhao M, Kircher MF, Josephson L, Weissleder R

Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake

Bioconjug Chem. 2002;13:840-4 - PMID: 12121140

Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes

Bioconjug Chem. 2002;13:554-60 - PMID: 12009946

Lin Y, Weissleder R, Tung CH

Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation

Bioconjug Chem. 2002;13:605-10 - PMID: 12009952

Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr

Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture

Bioconjug Chem. 2002;13:122-7 - PMID: 11792187

Hogemann D, Ntziachristos V, Josephson L, Weissleder R

High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes

Bioconjug Chem. 2002;13:116-21 - PMID: 11792186

Wunderbaldinger P, Josephson L, Weissleder R

Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles

Bioconjug Chem. 2002;13:264-8 - PMID: 11906263

Kang HW, Weissleder R, Bogdanov A Jr

Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro

Amino Acids. 2002;23:301-8 - PMID: 12373551

Ntziachristos V, Weissleder R

Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media

Med Phys. 2002;29:803-9 - PMID: 12033576

Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R

Detection of lymph node metastases by contrast-enhanced MRI in an experimental model

Magn Reson Med. 2002;47:292-7 - PMID: 11810672

Moore, A, Sun PZ, Cory D, Hogemann D, Weissleder R, Lipes MA

MRI of insulitis in autoimmune diabetes

Magn Reson Med. 2002;47:751-8 - PMID: 11948737

Kircher MF, Josephson L, Weissleder R

Ratio imaging of enzyme activity using dual wavelength optical reporters

Mol Imaging. 2002;1:89-95 - PMID: 12920849

Bogdanov A Jr, Matuszewski L, Bremer C, Petrovsky A, Weissleder R

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets

Mol Imaging. 2002;1:16-23 - PMID: 12920857

Schellenberger EA, Bogdanov A Jr, Hogemann D, Tait J, Weissleder R, Josephson L

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI

Mol Imaging. 2002;1:102-7 - PMID: 12920851

Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R

Coded aperture nuclear scintigraphy: a novel small animal imaging technique

Mol Imaging. 2002;1:344-53 - PMID: 12926230

Ntziachristos, V, Bremer C, Graves EE, Ripoll J, Weissleder R

In vivo tomographic imaging of near-infrared fluorescent probes

Mol Imaging. 2002;1:82-8 - PMID: 12920848

Tung CH, Lin Y, Moon WK, Weissleder R

A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging

Chembiochem. 2002;3:784-6 - PMID: 12203978

Tung CH, Gerszten RE, Jaffer FA, Weissleder R

A novel near-infrared fluorescence sensor for detection of thrombin activation in blood

Chembiochem. 2002;3:207-11 - PMID: 11921399

Tung CH, Mueller S, Weissleder R

Novel branching membrane translocational peptide as gene delivery vector

Bioorg Med Chem. 2002;10:3609-14 - PMID: 12213476

Pham W, Weissleder R, Tung CH

Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives.

Tetrahedron Lett. 2002;43(1):19-20 - PMID: 20740048 - PMCID: PMC2926969

Kim YR, Savellano MD, Weissleder R, Bogdanov A Jr

Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study

Technol Cancer Res T. 2002;1:489-95 - PMID: 12625776

Ntziachristos, V, Bremer C, Tung C, Weissleder R

Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT)

Acad Radiol. 2002;9 Suppl 2:S323-5 - PMID: 12188262

Bremer C, Tung CH, Weissleder R

Molecular imaging of MMP expression and therapeutic MMP inhibition

Acad Radiol. 2002;9 Suppl 2:S314-5 - PMID: 12188259

Mahmood U, Weissleder R

Some tools for molecular imaging

Acad Radiol. 2002;9:629-31 - PMID: 12061735

Wunderbaldinger P, Josephson L, Weissleder R

Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents

Acad Radiol. 2002;9 Suppl 2:S304-6 - PMID: 12188255

Schellenberger EA, Hogemann D, Josephson L, Weissleder R

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI

Acad Radiol. 2002;9 Suppl 2:S310-1 - PMID: 12188257

Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R

MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer

Acad Radiol. 2002;9 Suppl 2:S312-3 - PMID: 12188258

Rabkin E, Hoerstrup S, Aikawa M, Mayer J, Schoen F

Evolution of cell phenotype and extracellular matrix in tissue-engineered heart valves during in-vitro maturation and in-vivo remodeling.

J Heart Valve Dis. 2002;11:308-14; discussion 314 - PMID: 12056720