Lab: Shah, Khalid

Date Posted: 2008-04-30

Description: Postdoctoral research position is available immediately in Molecular Neuroscience and Imaging Unit of Center for Molecular Imaging Research at Massachusetts General Hospital and Harvard Medical School. Our laboratory focuses on engineering neural stem cell based regulatable apoptotic and antiangiogenic therapies for gliomas. Inherently linked to the brain tumor therapy paradigm, we employ fluorescent/bioluminesecent imaging markers and optical imaging techniques to image stem cell fate and monitor the effect of therapeutic genes delivered to brain tumors. In an effort to develop combination therapies and sensitize glioma cells to therapeutic stem cells, we are also interested in altering the EGFR/PI3K/AKT signaling pathway that is frequently overactive in high grade gliomas.

Requirements: Applicants should have a PhD degree or equivalents, with experience in one or more of the following techniques such as neural stem cell biology, gene cloning, vector construction and animal surgeries.

We offer excellent training opportunities in a collaborative research environment including molecular biology, stem cell biology, gene delivery to brain tumors and imaging disciplines.

Please submit a CV and two references to: Dr. Khalid Shah @ kshah@helix.mgh.harvard.edu.