The Cardiovascular Molecular Imaging Program (CMIP) is a broad-based translational and clinical molecular imaging effort that aims to better understand the molecular basis of cardiovascular disease. An important focus of this work is to translate promising molecular imaging agents into the clinical arena to better diagnose, risk stratify, and treat human cardiovascular disease. We are actively utilizing an array of imaging readouts including optical imaging (specifically near infrared fluorescence), magnetic resonance imaging, integrated SPECT/CT imaging, optical coherence tomography and other intravascular imaging techniques. We are closely involved with molecular imaging chemistry efforts, the mouse imaging program, and the cellular imaging program at CMIR.